The combined use of electrocardiography, echocardiography and cardiac magnetic resonance imaging in left atrium evaluation among beta-thalassemia patients
نویسندگان
چکیده
Abstract Funding Acknowledgements Type of funding sources: None. Introduction Beta-thalassemia major (β-TM) patients are subjected to iron overload as a consequence chronic blood transfusions. The redundant affects, among other organs, the heart resulting in myocardial dysfunction. Iron deposition does not only affect ventricular myocardium but atrial well. According current practice, overall status is estimated by calculating T2* at middle section septum using cardiac magnetic resonance imaging (CMR). Current CMR technology limits direct estimation status. Purpose study evaluates left function novel echocardiographic techniques and correlates these findings with data. Methods 37 β-TM (mean age 41.17 years (SD = 8.33), 51.4% male), were electrocardiography, echocardiography P wave axis, PR segment duration, volume index (LAVI), strain reservoir phase (LASr) measured. Results No correlation between LASr (r 0.253, p 0.131) or LAVI 0.044, 0.796) found. However, was found parameters -0.676, <0.001). axis did correlate any parameter, while duration correlated -0.399, 0.015). Regression analysis revealed (r2 0.457, Conclusions suggests that despite undisputed contribution load estimation, it may be less accurate estimation. Considering limitations regarding thin right walls, our highlights role speckle tracking combination for more comprehensive evaluation patients. Correlation table 0,151 (p 0,373) 0,112 0.,508) -0,140 0,410) -0,117 0,489) 0,051 0,766) 0,278 0,096) -0,399 0,015) 0,044 0,796) 0,253 0,131) -0,676 <0,001) T2*: obtained (ml/m2) Figure.
منابع مشابه
Evaluation of tissue doppler echocardiography and T2* magnetic resonance imaging in iron load of patients with thalassemia major
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background: iron-mediated cardiomyopathy is the main complication of thalassemia major (tm) patients. therefore, there is an important clinical need in the early diagnosis and risk stratification of patients. the aim of this study was to evaluate the efficacy of tissue doppler imaging (tdi) to study cardiac iron overload in patients with tm using t2* magnetic resonance (mr) as the gold-standard...
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ژورنال
عنوان ژورنال: European Journal of Echocardiography
سال: 2021
ISSN: ['2047-2412', '2047-2404']
DOI: https://doi.org/10.1093/ehjci/jeaa356.159